CpG Islands reports potential CpG island regions
using the method described by Gardiner-Garden
and Frommer (1987). The calculation is performed using a 200 bp
window moving across the sequence at 1 bp intervals. CpG islands are
defined as sequence ranges where the Obs/Exp value is greater than
0.6 and the GC content is greater than 50%. The expected number of
CpG dimers in a window is calculated as the number of 'C's in the
window multiplied by the number of 'G's in the window, divided by
the window length. CpG islands are often found in the 5' regions of
vertebrate genes, therefore this program can be used to highlight
potential genes in genomic sequences.
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Manipulation Suite version 2. See the about
the Sequence Manipulation Suite page for more information
about individual Sequence Manipulation Suite programs.
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